ICSI

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            [blog_title] => Intracytoplasmic Sperm Injection (ICSI): Should You Opt for It?
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If you and your partner have been struggling with fertility issues, you may have come across various treatment options, including ICSI. But what exactly is ICSI, and is it the right choice for you? In this blog, we will explore the benefits, considerations and success rates of ICSI to help you make an informed decision on your path to parenthood.

What is ICSI?

ICSI is a specialised form of in vitro fertilisation (IVF) that addresses male infertility by directly injecting a single sperm into an egg. This procedure helps overcome challenges such as low sperm count, poor sperm motility or abnormal sperm shape. By bypassing natural barriers to fertilisation, ICSI increases the chances of successful fertilisation and subsequent pregnancy.

Benefits of ICSI

  1. Increased chances of fertilisation: ICSI offers hope to couples who have been struggling with male infertility factors. By directly injecting a healthy sperm into the egg, it improves the chances of successful fertilisation.
  2. Individualised approach: Unlike the traditional IVF procedure, where multiple sperm are introduced to an egg in a dish, ICSI allows for a more precise selection process. Your fertility doctor or embryologist can choose the best quality sperm for injection, increasing the likelihood of embryo development.
  3. Treatment for severe male infertility: ICSI can successfully treat severe male infertility issues such as low sperm count or abnormal sperm shape that may hinder natural fertilisation.
  4. Genetic testing: ICSI also allows for preimplantation genetic testing, which can help identify and select embryos free from certain genetic conditions or chromosomal abnormalities.

Considerations for ICSI

While ICSI offers several benefits, it's essential to consider certain factors before opting for this procedure:

  1. Cost: ICSI is a more specialised technique compared to the traditional IVF procedure, and it may be more expensive as a result. It is important to discuss the financial aspect with your fertility doctor and ensure you have a clear understanding of the costs involved.
  2. Ethical considerations: Some individuals may have ethical concerns about the selection process involved in ICSI. It is crucial to have open conversations with your partner and fertility doctor to address any concerns you may have.
  3. Limited sperm sample: In some cases, there may be a limited number of viable sperm available for injection. This could be due to low sperm count or poor sperm quality. Your fertility specialist will assess the suitability of ICSI based on the available sample.
  4. No guarantee of success: While ICSI can significantly improve the chances of fertilisation, it does not guarantee pregnancy. It is important to manage expectations and understand that multiple factors contribute to successful conception and pregnancy.

Success rates of ICSI

The success rates of ICSI vary depending on several factors, including the age of the woman, the quality of the eggs and sperm and overall health factors. According to studies conducted in India, the success rates for ICSI can range from 30% to 50%, with higher success rates observed in younger women and couples without additional fertility issues.

In conclusion, ICSI can be a viable option for couples dealing with male infertility factors. However, it's crucial to consult with a fertility specialist who can assess your specific situation and guide you through the decision-making process. If you think ICSI may be the right choice for you and your partner, reach out to Apollo Fertility, a renowned brand in the field of healthcare that offers comprehensive fertility treatments and supports couples on their journey to parenthood.

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If you and your partner have been struggling with fertility issues, you may have come across various treatment options, including ICSI. But what exactly is ICSI, and is it the right choice for you? In this blog, we will explore the benefits, considerations and success rates of ICSI to help you make an informed decision on your path to parenthood.

What is ICSI?

ICSI is a specialised form of in vitro fertilisation (IVF) that addresses male infertility by directly injecting a single sperm into an egg. This procedure helps overcome challenges such as low sperm count, poor sperm motility or abnormal sperm shape. By bypassing natural barriers to fertilisation, ICSI increases the chances of successful fertilisation and subsequent pregnancy.

Benefits of ICSI

  1. Increased chances of fertilisation: ICSI offers hope to couples who have been struggling with male infertility factors. By directly injecting a healthy sperm into the egg, it improves the chances of successful fertilisation.
  2. Individualised approach: Unlike the traditional IVF procedure, where multiple sperm are introduced to an egg in a dish, ICSI allows for a more precise selection process. Your fertility doctor or embryologist can choose the best quality sperm for injection, increasing the likelihood of embryo development.
  3. Treatment for severe male infertility: ICSI can successfully treat severe male infertility issues such as low sperm count or abnormal sperm shape that may hinder natural fertilisation.
  4. Genetic testing: ICSI also allows for preimplantation genetic testing, which can help identify and select embryos free from certain genetic conditions or chromosomal abnormalities.

Considerations for ICSI

While ICSI offers several benefits, it's essential to consider certain factors before opting for this procedure:

  1. Cost: ICSI is a more specialised technique compared to the traditional IVF procedure, and it may be more expensive as a result. It is important to discuss the financial aspect with your fertility doctor and ensure you have a clear understanding of the costs involved.
  2. Ethical considerations: Some individuals may have ethical concerns about the selection process involved in ICSI. It is crucial to have open conversations with your partner and fertility doctor to address any concerns you may have.
  3. Limited sperm sample: In some cases, there may be a limited number of viable sperm available for injection. This could be due to low sperm count or poor sperm quality. Your fertility specialist will assess the suitability of ICSI based on the available sample.
  4. No guarantee of success: While ICSI can significantly improve the chances of fertilisation, it does not guarantee pregnancy. It is important to manage expectations and understand that multiple factors contribute to successful conception and pregnancy.

Success rates of ICSI

The success rates of ICSI vary depending on several factors, including the age of the woman, the quality of the eggs and sperm and overall health factors. According to studies conducted in India, the success rates for ICSI can range from 30% to 50%, with higher success rates observed in younger women and couples without additional fertility issues.

In conclusion, ICSI can be a viable option for couples dealing with male infertility factors. However, it's crucial to consult with a fertility specialist who can assess your specific situation and guide you through the decision-making process. If you think ICSI may be the right choice for you and your partner, reach out to Apollo Fertility, a renowned brand in the field of healthcare that offers comprehensive fertility treatments and supports couples on their journey to parenthood.

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Intracytoplasmic Sperm Injection (ICSI): Should You Opt for It?

Intracytoplasmic Sperm Injection (ICSI): Should You Opt for It?

March 11, 2024

If you and your partner have been struggling with fertility issues, yo...

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The issue of infertility has long existed. It is a disorder of the male or female reproductive system characterized by the inability to conceive after 12 months or more of consistent, unprotected sexual activity. However, as the world has modernized, people have begun to discuss infertility openly. As a result, more new techniques for addressing this problem are emerging.

One such advanced technology is the intra-cytoplasmic sperm injection (ICSI).

What is ICSI treatment?

ICSI treatment involves injecting the sperm cell directly into the mature egg’s cytoplasm. It is among the most effective artificial treatment options for male infertility-related issues, with a success rate of 85%.

In cases of male infertility brought on by low sperm count, low motility, azoospermia, or erectile dysfunction, ICSI IVF is frequently adopted by couples as it improves the chances of getting pregnant.

What is a successful ICSI procedure?

● Stimulation of the ovaries

A woman’s ovary produces one egg each month through a normal menstrual cycle. However, multiple eggs must be extracted to improve the success rate of ICSI. Thus, the stimulation of the ovaries is necessary for there to be more than one egg accessible.

During the process, a woman receives hormone injections for approximately 8 to 14 days to encourage the ovaries to produce mature eggs.

● Egg & sperm retrieval

Several eggs are extracted from a woman’s ovaries using a thin needle and ultrasonography probe. Although the egg retrieval process is not painful, it could result in minor bruising or soreness.

For the sperm retrieval process, either the man provides a sperm sample by ejaculating into a cup, or the sperm is removed surgically. In some circumstances, the sperm retrieval operation is carried out early, and the sperm is frozen till the procedure.

● Fertilisation

Once the semen sample has been obtained, it is washed, and a single sperm is extracted. Then, a sperm is injected directly into an egg using a hollow, extremely thin needle. This step eliminates the necessity for the sperm to swim through the cervical fluid. A sperm might take up to 24 hours to fertilize an egg and produce an embryo.

● Embryo development

The fertilized embryos will be kept in a lab for up to 6 days to observe their growth and development. Since not every fertilized embryo will be placed in the woman’s womb, this stage is crucial for selecting the healthiest and most viable embryos.

● Embryo transfer

One or two embryos are chosen and transferred to the woman’s womb using an ultrasound-guided catheter once the embryo reaches a specific stage of development. This step could occur two days or five days after fertilization.

Two weeks after the fertilized egg has been transferred to the womb, it is typically recommended to take a pregnancy test.

Take Away

ICSI treatment helps infertile couples have a genetic child, especially when the male partner is infertile. The ICSI procedure has a great success rate and reduces the risks of the infant having physical or mental problems.
Remember, speaking with a doctor before opting for any medical procedure is advised.

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The issue of infertility has long existed. It is a disorder of the male or female reproductive system characterized by the inability to conceive after 12 months or more of consistent, unprotected sexual activity. However, as the world has modernized, people have begun to discuss infertility openly. As a result, more new techniques for addressing this problem are emerging.

One such advanced technology is the intra-cytoplasmic sperm injection (ICSI).

What is ICSI treatment?

ICSI treatment involves injecting the sperm cell directly into the mature egg’s cytoplasm. It is among the most effective artificial treatment options for male infertility-related issues, with a success rate of 85%.

In cases of male infertility brought on by low sperm count, low motility, azoospermia, or erectile dysfunction, ICSI IVF is frequently adopted by couples as it improves the chances of getting pregnant.

What is a successful ICSI procedure?

● Stimulation of the ovaries

A woman’s ovary produces one egg each month through a normal menstrual cycle. However, multiple eggs must be extracted to improve the success rate of ICSI. Thus, the stimulation of the ovaries is necessary for there to be more than one egg accessible.

During the process, a woman receives hormone injections for approximately 8 to 14 days to encourage the ovaries to produce mature eggs.

● Egg & sperm retrieval

Several eggs are extracted from a woman’s ovaries using a thin needle and ultrasonography probe. Although the egg retrieval process is not painful, it could result in minor bruising or soreness.

For the sperm retrieval process, either the man provides a sperm sample by ejaculating into a cup, or the sperm is removed surgically. In some circumstances, the sperm retrieval operation is carried out early, and the sperm is frozen till the procedure.

● Fertilisation

Once the semen sample has been obtained, it is washed, and a single sperm is extracted. Then, a sperm is injected directly into an egg using a hollow, extremely thin needle. This step eliminates the necessity for the sperm to swim through the cervical fluid. A sperm might take up to 24 hours to fertilize an egg and produce an embryo.

● Embryo development

The fertilized embryos will be kept in a lab for up to 6 days to observe their growth and development. Since not every fertilized embryo will be placed in the woman’s womb, this stage is crucial for selecting the healthiest and most viable embryos.

● Embryo transfer

One or two embryos are chosen and transferred to the woman’s womb using an ultrasound-guided catheter once the embryo reaches a specific stage of development. This step could occur two days or five days after fertilization.

Two weeks after the fertilized egg has been transferred to the womb, it is typically recommended to take a pregnancy test.

Take Away

ICSI treatment helps infertile couples have a genetic child, especially when the male partner is infertile. The ICSI procedure has a great success rate and reduces the risks of the infant having physical or mental problems.
Remember, speaking with a doctor before opting for any medical procedure is advised.

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What is the Procedure for a Successful ICSI?

What is the Procedure for a Successful ICSI?

November 30, 2022

The issue of infertility has long existed. It is a disorder of the...

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            [blog_title] => Decoding ICSI A Step-By-Step Breakdown
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When it comes to treating sperm-related infertility in couples, intracytoplasmic sperm injection (ICSI) is used. A part of an assisted reproductive technology (ART), the ICSI treatment helps increase the chances of fertilization through injection of a high-quality sperm into an ovulated egg during the in vitro fertilization procedure. Once the embryo is hatched, it is carefully placed in the uterus of a woman partner.

With ICSI, severe male infertility, where there is little or no sperm released in the semen, is treated. The sperm collected from the male reproductive system are immature and unable to move about. Intracytoplasmic sperm injection can help you here to fertilize the egg.

When Should You Go for Intracytoplasmic Sperm Injection Treatment?

ICSI is performed in conjunction with in vitro fertilization (IVF) after repeated failures in conventional IVF cycles owing to severe male infertility. It is also commonly used when frozen eggs are used for fertilization, as well as for PGT or preimplantation genetic testing. Most fertility clinics today recommend ICSI with every IVF cycle despite several arguments against using it regularly. ICSI is used with IVF in severe male infertility cases such as:

  • Extremely low sperm count or oligospermia
  • Poor sperm movement or asthenozoospermia
  • Abnormally shaped sperm or teratozoospermia 

In case the male partner, who is producing sperm, have no sperm in ejaculation, testicular sperm extraction or TESE is used to retrieve his sperm. Where TESE is used to collect sperm, it asks for the use of ICSI to help fertilization. Other than male infertility, ICSI is considered to be a good option for: 

  1. The Next IVF Cycle if the Previous IVF Cycles Have No or Very Few Fertilized Eggs

There are instances when the IVF cycle fails owing to no or fewer fertilized eggs despite the retrieval of sufficient number of matured eggs and availability of healthy sperm. Your doctor may suggest ICSI in the next IVF cycle to increase the chances or pregnancy. This is usually done after discussing with you.

  1.  An IVF Cycle Where Frozen Sperm Is Used

ICSI is recommended in the IVF phase in case the thawed sperm is not active. Studies show that the outcomes of using ICSI in frozen sperm gives the same pregnancy success rate as with the fresh ones.

  1. Genetic Screening Using PGD

When preimplantation genetic diagnosis (PGD) is used for genetic screening of fertilized egg or embryos, regular IVF technique may lead to the sperm cells, which are not part of the fertilization, to be around the embryo. This may affect the PGD results. PGD testing is generally suggested if a genetic condition is present in your family, and you want to reduce the chance of passing it on to the baby.  The IVF with PGD procedures recommend ICSI as a suitable method for fertilization.

  1. A Fertilization Procedure Using Frozen Oocytes

Some women prefer to freeze their eggs when they are young for use later. Oocyte Vitrification can harden the egg’s outer shell making fertilization of the egg difficult in the IVF procedure. The ICSI treatment can help solve this problem for the healthy sperm is directly injected into the thawed egg to enable easy fertilization.

  1. Using In Vitro Maturation or IVM

The in vitro maturation or IVM technique is used, in which the eggs, before they fully mature, are collected from the ovaries to allow them to go for maturation in the lab. In the traditional IVF cycle, the IVM eggs may not fertilize, even if high-quality sperm are used. Nevertheless, using ICSI with IVF gives better chances for fertilization of the eggs retrieved using the IVM procedure. There are not enough studies conducted in this line.

When the situations mentioned above prove that IVF with ICSI can be the best available option to increase the pregnancy success rates through IVF, there are some controversies on using ICSI in tandem with IVF in cases such as:

  • Unexplained Infertility: There are no studies conducted to show that ICSI can help improve pregnancy rates in couples with unexplained infertility. Nevertheless, ICSI is suggested by doctors to try every possible way of helping couples become pregnant. 
  • Advanced Maternal Age: ICSI is sometimes recommended for women who are in advanced maternal age (AMA). There are no studies to show that AMA will affect fertilization rates, and hence, the use of ICSI in this case is hard to justify.
  • ICSI for Every Couple with Infertility:  Some fertility specialists are of the opinion that every couple with fertility problems should undergo the ICSI treatment to eliminate fertilization failure. Research shows that out of every 33 patients only one would find IVF-ICSI beneficial. The others would undergo the treatment without receiving any benefit.

Though the ICSI treatment provides better fertilization rates of eggs, using it along with IVF depends on your circumstances, and it is up to your fertility specialist.

Apollo Fertility Services & Treatments

HSG Test Fertility Treatments
Endometriosis Treatment Cryopreservation Treatment
Reproductive Surgery Treatment Laser Assisted Hatching

 

Apollo Fertility Centres

Best IVF Centre in Delhi Best Fertility Centre in Chennai
Best IVF Centre in Bangalore Best Fertility Centre in Hyderabad
Best IVF Centre in Kolkata Best IVF Centre in Mumbai
Best IVF Centre in Noida Best IVF Centre in Thane
Best IVF Centre in Varanasi Best IVF Centre in Guwahati
Best IVF Centre in Ghaziabad Best IVF Centre in Amritsar
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When it comes to treating sperm-related infertility in couples, intracytoplasmic sperm injection (ICSI) is used. A part of an assisted reproductive technology (ART), the ICSI treatment helps increase the chances of fertilization through injection of a high-quality sperm into an ovulated egg during the in vitro fertilization procedure. Once the embryo is hatched, it is carefully placed in the uterus of a woman partner.

With ICSI, severe male infertility, where there is little or no sperm released in the semen, is treated. The sperm collected from the male reproductive system are immature and unable to move about. Intracytoplasmic sperm injection can help you here to fertilize the egg.

When Should You Go for Intracytoplasmic Sperm Injection Treatment?

ICSI is performed in conjunction with in vitro fertilization (IVF) after repeated failures in conventional IVF cycles owing to severe male infertility. It is also commonly used when frozen eggs are used for fertilization, as well as for PGT or preimplantation genetic testing. Most fertility clinics today recommend ICSI with every IVF cycle despite several arguments against using it regularly. ICSI is used with IVF in severe male infertility cases such as:

  • Extremely low sperm count or oligospermia
  • Poor sperm movement or asthenozoospermia
  • Abnormally shaped sperm or teratozoospermia 

In case the male partner, who is producing sperm, have no sperm in ejaculation, testicular sperm extraction or TESE is used to retrieve his sperm. Where TESE is used to collect sperm, it asks for the use of ICSI to help fertilization. Other than male infertility, ICSI is considered to be a good option for: 

  1. The Next IVF Cycle if the Previous IVF Cycles Have No or Very Few Fertilized Eggs

There are instances when the IVF cycle fails owing to no or fewer fertilized eggs despite the retrieval of sufficient number of matured eggs and availability of healthy sperm. Your doctor may suggest ICSI in the next IVF cycle to increase the chances or pregnancy. This is usually done after discussing with you.

  1.  An IVF Cycle Where Frozen Sperm Is Used

ICSI is recommended in the IVF phase in case the thawed sperm is not active. Studies show that the outcomes of using ICSI in frozen sperm gives the same pregnancy success rate as with the fresh ones.

  1. Genetic Screening Using PGD

When preimplantation genetic diagnosis (PGD) is used for genetic screening of fertilized egg or embryos, regular IVF technique may lead to the sperm cells, which are not part of the fertilization, to be around the embryo. This may affect the PGD results. PGD testing is generally suggested if a genetic condition is present in your family, and you want to reduce the chance of passing it on to the baby.  The IVF with PGD procedures recommend ICSI as a suitable method for fertilization.

  1. A Fertilization Procedure Using Frozen Oocytes

Some women prefer to freeze their eggs when they are young for use later. Oocyte Vitrification can harden the egg’s outer shell making fertilization of the egg difficult in the IVF procedure. The ICSI treatment can help solve this problem for the healthy sperm is directly injected into the thawed egg to enable easy fertilization.

  1. Using In Vitro Maturation or IVM

The in vitro maturation or IVM technique is used, in which the eggs, before they fully mature, are collected from the ovaries to allow them to go for maturation in the lab. In the traditional IVF cycle, the IVM eggs may not fertilize, even if high-quality sperm are used. Nevertheless, using ICSI with IVF gives better chances for fertilization of the eggs retrieved using the IVM procedure. There are not enough studies conducted in this line.

When the situations mentioned above prove that IVF with ICSI can be the best available option to increase the pregnancy success rates through IVF, there are some controversies on using ICSI in tandem with IVF in cases such as:

  • Unexplained Infertility: There are no studies conducted to show that ICSI can help improve pregnancy rates in couples with unexplained infertility. Nevertheless, ICSI is suggested by doctors to try every possible way of helping couples become pregnant. 
  • Advanced Maternal Age: ICSI is sometimes recommended for women who are in advanced maternal age (AMA). There are no studies to show that AMA will affect fertilization rates, and hence, the use of ICSI in this case is hard to justify.
  • ICSI for Every Couple with Infertility:  Some fertility specialists are of the opinion that every couple with fertility problems should undergo the ICSI treatment to eliminate fertilization failure. Research shows that out of every 33 patients only one would find IVF-ICSI beneficial. The others would undergo the treatment without receiving any benefit.

Though the ICSI treatment provides better fertilization rates of eggs, using it along with IVF depends on your circumstances, and it is up to your fertility specialist.

Apollo Fertility Services & Treatments

HSG Test Fertility Treatments
Endometriosis Treatment Cryopreservation Treatment
Reproductive Surgery Treatment Laser Assisted Hatching

 

Apollo Fertility Centres

Best IVF Centre in Delhi Best Fertility Centre in Chennai
Best IVF Centre in Bangalore Best Fertility Centre in Hyderabad
Best IVF Centre in Kolkata Best IVF Centre in Mumbai
Best IVF Centre in Noida Best IVF Centre in Thane
Best IVF Centre in Varanasi Best IVF Centre in Guwahati
Best IVF Centre in Ghaziabad Best IVF Centre in Amritsar
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Decoding ICSI A Step-By-Step Breakdown

Decoding ICSI A Step-By-Step Breakdown

October 12, 2022

When it comes to treating sperm-re...

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            [blog_title] => ICSI or IVF: Which Treatment Should You Opt for?
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The field of infertility has seen an unprecedented advancement in the last few decades. The physiology of ovulation is better understood today through the development of better diagnosis methods. Whether ICSI or IVF, it helps you have a baby using different fertility treatments. 

Advanced reproductive technologies (ART), which is the foundation of modern infertility management, have given hope to the parents who want to get pregnant and have a child. Though in vitro fertilization (IVF), a conventional method, has been a treatment for these parents, the emergence of intracytoplasmic sperm injection (ICSI) has made it choose over IVF owing to its increasing use recently. 

How Is ICSI Different from IVF?

Intracytoplasmic sperm injection or ICSI is a treatment method, in which a single, healthy sperm is chosen and carefully injected into the egg by an embryologist in a laboratory. With this technique, fertilization of eggs is attained in the lab and then, the embryo is transferred to the uterus or womb. 

The IVF treatment, on the other hand, also helps women become pregnant through fertilization of eggs and development of embryos and implantation. The process involves medication to make eggs mature, which are taken out for fertilization in a specialized lab. When the eggs are fertilized, the doctor transfers one of more eggs to the uterus. Both ICSI IVF is performed by implanting the embryo(s) in the lining of a woman’s uterus, and only the initial process differs.

Also, Read: Success Rate Of ICSI

Whether ICSI or IVF – Which Should You Consider?

Research shows that both ICSI and IVF are effective depending on the circumstances. The introduction of IVF in 1980s assisted several couples, who had been infertile, have babies; however, the treatment was not successful with couples, in which the men had low sperm count. This led to the development of ICSI, which was effective even in couples with male factor infertility. Despite the widespread use of intracytoplasmic sperm injection procedure in couples with non-male factor infertility, its effectiveness in these patients still requires much evidence for confirmation.

When ICSI is considered the best option in the cases of failure of fertilization owing to immunological infertility and ejaculatory dysfunction, its safety is not guaranteed. The procedure if used unnecessarily has worked out expensive and unethical. However, this does not apply to patients with severe male-factor infertility. Research studies show ICSI as a highly advanced treatment procedure for male infertility and its use has extended recently for non-male factor infertility too. The risk of oocytes getting damaged is possible in ICSI and may reduce the chances of fertilization, as well as pregnancy.  

Some comparison studies of ICSI IVF showed that the fertilization rates, as well as the implantation rates were considerably higher in the IVF procedure than the ICSI procedure. Similarly, it was found that the percentage of chemical and clinical pregnancy was also statistically higher in IVF than that in ICSI. IVF was considered superior to ICSI in some studies associated with the normoresponder patients with non-male factor because of no improvement in the percentages of fertilization, implantation and clinical pregnancy among these patients in ICSI. 

This raises a question as to when ICSI is used and the results of the study show that it is especially in the case of severe male-factor problems instead of non-male factor infertility, and further, it did not relate to improved fertilization and pregnancy rates.

Also, Read: Things You Need to Know About ICSI

For Whom Should ICSI Considered for:

The couples with male-factor infertility, especially in which case the man’s semen is regarded an abnormal semen analysis, ICSI is absolutely essential. Some reasons why couples decide to go for ICSI are:

  • Failed fertilization in the last IVF treatment
  • Unexplained infertility
  • Very low sperm count
  • Sperms fail to move properly
  • High percentage of abnormal sperms
  • Retrieving sperms by electro-ejaculation or retrieving directly from the testicles (TESA) or from the epididymis (PESA)
  • In the case of frozen sperms 
  • Semen with high levels of antibodies

For Whom Should IVF Considered for:

You May Be Asked to Opt For IVF in the Following Cases:

  • Ovulation problems because of hormone imbalance, which is called polycystic ovarian syndrome (PCOS).
  • Low sperm count
  • Problems associated with fallopian tubes
  • In case one of you is sterilized 
  • Avoid any genetic disorders in the baby
  • Endometriosis

Various Risks Involved with ICSI and IVF

Both ICSI and IVF are recommended by doctors based on the circumstances such as emotional difficulties and psychological demand. However, both these treatments are associated with risks and they are:

  • In the case of hormone medications, the ovaries swell owing to excess hormones causing ovarian hyperstimulation syndrome (OHSS)
  • Multiple birth i.e., giving birth to twins and triplets
  • Premature labor 
  • Caesarean delivery
  • Low birth weight
  • A low risk of birth defects 

In conclusion, choosing between ICSI and IVF is primarily based on the initial infertility test. The other factors to be considered are your age and medical history, as well as the results of previous treatment cycles you might have had earlier.

Also, Read: Why Couples Should Opt for IVF

Apollo Fertility Services & Treatments

IUI Treatment Ovulation Induction Treatment
Endometriosis Treatment HSG Treatment
Oocyte Vitrification Treatment Laser Assisted Hatching Treatment
Reproductive Surgery Treatment Cryopreservation Treatment

 

Apollo Fertility Centres

IVF Centre in Delhi Fertility Centre in Chennai
IVF Centre in Bangalore Fertility Centre in Hyderabad
IVF Centre in Kolkata IVF Centre in Mumbai
IVF Centre in Noida IVF Centre in Thane
IVF Centre in Varanasi IVF Centre in Guwahati
IVF Centre in Ghaziabad IVF Centre in Amritsar
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The field of infertility has seen an unprecedented advancement in the last few decades. The physiology of ovulation is better understood today through the development of better diagnosis methods. Whether ICSI or IVF, it helps you have a baby using different fertility treatments. 

Advanced reproductive technologies (ART), which is the foundation of modern infertility management, have given hope to the parents who want to get pregnant and have a child. Though in vitro fertilization (IVF), a conventional method, has been a treatment for these parents, the emergence of intracytoplasmic sperm injection (ICSI) has made it choose over IVF owing to its increasing use recently. 

How Is ICSI Different from IVF?

Intracytoplasmic sperm injection or ICSI is a treatment method, in which a single, healthy sperm is chosen and carefully injected into the egg by an embryologist in a laboratory. With this technique, fertilization of eggs is attained in the lab and then, the embryo is transferred to the uterus or womb. 

The IVF treatment, on the other hand, also helps women become pregnant through fertilization of eggs and development of embryos and implantation. The process involves medication to make eggs mature, which are taken out for fertilization in a specialized lab. When the eggs are fertilized, the doctor transfers one of more eggs to the uterus. Both ICSI IVF is performed by implanting the embryo(s) in the lining of a woman’s uterus, and only the initial process differs.

Also, Read: Success Rate Of ICSI

Whether ICSI or IVF – Which Should You Consider?

Research shows that both ICSI and IVF are effective depending on the circumstances. The introduction of IVF in 1980s assisted several couples, who had been infertile, have babies; however, the treatment was not successful with couples, in which the men had low sperm count. This led to the development of ICSI, which was effective even in couples with male factor infertility. Despite the widespread use of intracytoplasmic sperm injection procedure in couples with non-male factor infertility, its effectiveness in these patients still requires much evidence for confirmation.

When ICSI is considered the best option in the cases of failure of fertilization owing to immunological infertility and ejaculatory dysfunction, its safety is not guaranteed. The procedure if used unnecessarily has worked out expensive and unethical. However, this does not apply to patients with severe male-factor infertility. Research studies show ICSI as a highly advanced treatment procedure for male infertility and its use has extended recently for non-male factor infertility too. The risk of oocytes getting damaged is possible in ICSI and may reduce the chances of fertilization, as well as pregnancy.  

Some comparison studies of ICSI IVF showed that the fertilization rates, as well as the implantation rates were considerably higher in the IVF procedure than the ICSI procedure. Similarly, it was found that the percentage of chemical and clinical pregnancy was also statistically higher in IVF than that in ICSI. IVF was considered superior to ICSI in some studies associated with the normoresponder patients with non-male factor because of no improvement in the percentages of fertilization, implantation and clinical pregnancy among these patients in ICSI. 

This raises a question as to when ICSI is used and the results of the study show that it is especially in the case of severe male-factor problems instead of non-male factor infertility, and further, it did not relate to improved fertilization and pregnancy rates.

Also, Read: Things You Need to Know About ICSI

For Whom Should ICSI Considered for:

The couples with male-factor infertility, especially in which case the man’s semen is regarded an abnormal semen analysis, ICSI is absolutely essential. Some reasons why couples decide to go for ICSI are:

  • Failed fertilization in the last IVF treatment
  • Unexplained infertility
  • Very low sperm count
  • Sperms fail to move properly
  • High percentage of abnormal sperms
  • Retrieving sperms by electro-ejaculation or retrieving directly from the testicles (TESA) or from the epididymis (PESA)
  • In the case of frozen sperms 
  • Semen with high levels of antibodies

For Whom Should IVF Considered for:

You May Be Asked to Opt For IVF in the Following Cases:

  • Ovulation problems because of hormone imbalance, which is called polycystic ovarian syndrome (PCOS).
  • Low sperm count
  • Problems associated with fallopian tubes
  • In case one of you is sterilized 
  • Avoid any genetic disorders in the baby
  • Endometriosis

Various Risks Involved with ICSI and IVF

Both ICSI and IVF are recommended by doctors based on the circumstances such as emotional difficulties and psychological demand. However, both these treatments are associated with risks and they are:

  • In the case of hormone medications, the ovaries swell owing to excess hormones causing ovarian hyperstimulation syndrome (OHSS)
  • Multiple birth i.e., giving birth to twins and triplets
  • Premature labor 
  • Caesarean delivery
  • Low birth weight
  • A low risk of birth defects 

In conclusion, choosing between ICSI and IVF is primarily based on the initial infertility test. The other factors to be considered are your age and medical history, as well as the results of previous treatment cycles you might have had earlier.

Also, Read: Why Couples Should Opt for IVF

Apollo Fertility Services & Treatments

IUI Treatment Ovulation Induction Treatment
Endometriosis Treatment HSG Treatment
Oocyte Vitrification Treatment Laser Assisted Hatching Treatment
Reproductive Surgery Treatment Cryopreservation Treatment

 

Apollo Fertility Centres

IVF Centre in Delhi Fertility Centre in Chennai
IVF Centre in Bangalore Fertility Centre in Hyderabad
IVF Centre in Kolkata IVF Centre in Mumbai
IVF Centre in Noida IVF Centre in Thane
IVF Centre in Varanasi IVF Centre in Guwahati
IVF Centre in Ghaziabad IVF Centre in Amritsar
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ICSI or IVF: Which Treatment Should You Opt for?

ICSI or IVF: Which Treatment Should You Opt for?

September 7, 2022

The field of infertility has seen ...

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Infertility has been a problem for a long time, but it has only recently begun to be discussed. Today, there are quite a few ways that have been discovered in order to deal with infertility-related issues. IVF is the most common and well-known form of assisted artificial reproduction. However, many other methods such as ICSI too are gaining popularity and have a higher success rate, reportedly. It is commonly referred to as ICSI or IVF Treatment because it is not entirely separate from IVF; it simply includes some additional steps than IVF.

‍What Is ICSI?

‍ICSI is an abbreviation for intracytoplasmic sperm injection. The process is as follows: The male’s sperm is extracted, the best sperm is selected, and then artificially injected into the egg for fertilization. It is one of the most effective artificial treatment methods for infertility issues.

Reportedly, ICSI has a success rate of 80 to 85 percent. This means that approximately eight out of ten eggs will fertilize normally.

Also, Read: Types of Infertility

When Is ICSI Suggested?

ICSI is recommended in the following situations:

  • The sperm count is extremely low.
  • Sperms with unusual shapes
  • The couple does not wish to use a sperm donor.
  • It is necessary to avoid extremely specific genetic disorders.
  • The male has issues with ejaculation.

What Is the ICSI Procedure? 

‍ICSI process consists of five major steps: 

  1. Hormone regulation to allow the woman to produce more than one egg per month. This is accomplished through injections.
  2. A minor procedure is used to extract eggs from a woman’s ovaries.
  3. Ejaculation is used to extract sperm from males; it is preferable if the sperm is collected on the day of the procedure. The best sperm is then selected for the procedure after being filtered.
  4. For fertilization, the selected sperm is manually injected into the egg.
  5. A catheter is then used to insert the fertilized egg into the woman’s uterus.‍

Also, Read: Things You Need to Know About ICSI

ICSI Treatment Cost in India

Fertility or reproductive procedures are now usually prohibitively expensive in other parts of the world. However, depending on which medical institution and healthcare centre you choose, the procedure can be quite affordable in India.

ICSI is a procedure that occurs in multiple cycles, each of which has additional costs that must be paid for separately. The minimum ICSI treatment cost in India is Rs. 2,40,000 to Rs. 2,50,000 per cycle. This only includes the standard methods and techniques.

Many couples have been able to conceive healthy babies thanks to assisted reproductive systems. During the treatment cycles, a patient can feel more relaxed with the help of surgical treatment and maintenance. We strongly advise people to take and follow the doctor’s advice, as well as to maintain open and honest communication with the channel. A good working relationship with a specialist can help avoid risks. Doctors will also advise you on precautionary measures that you should take while undergoing the process.

Also, Read: Why Couples Should Opt for IVF

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Infertility has been a problem for a long time, but it has only recently begun to be discussed. Today, there are quite a few ways that have been discovered in order to deal with infertility-related issues. IVF is the most common and well-known form of assisted artificial reproduction. However, many other methods such as ICSI too are gaining popularity and have a higher success rate, reportedly. It is commonly referred to as ICSI or IVF Treatment because it is not entirely separate from IVF; it simply includes some additional steps than IVF.

‍What Is ICSI?

‍ICSI is an abbreviation for intracytoplasmic sperm injection. The process is as follows: The male’s sperm is extracted, the best sperm is selected, and then artificially injected into the egg for fertilization. It is one of the most effective artificial treatment methods for infertility issues.

Reportedly, ICSI has a success rate of 80 to 85 percent. This means that approximately eight out of ten eggs will fertilize normally.

Also, Read: Types of Infertility

When Is ICSI Suggested?

ICSI is recommended in the following situations:

  • The sperm count is extremely low.
  • Sperms with unusual shapes
  • The couple does not wish to use a sperm donor.
  • It is necessary to avoid extremely specific genetic disorders.
  • The male has issues with ejaculation.

What Is the ICSI Procedure? 

‍ICSI process consists of five major steps: 

  1. Hormone regulation to allow the woman to produce more than one egg per month. This is accomplished through injections.
  2. A minor procedure is used to extract eggs from a woman’s ovaries.
  3. Ejaculation is used to extract sperm from males; it is preferable if the sperm is collected on the day of the procedure. The best sperm is then selected for the procedure after being filtered.
  4. For fertilization, the selected sperm is manually injected into the egg.
  5. A catheter is then used to insert the fertilized egg into the woman’s uterus.‍

Also, Read: Things You Need to Know About ICSI

ICSI Treatment Cost in India

Fertility or reproductive procedures are now usually prohibitively expensive in other parts of the world. However, depending on which medical institution and healthcare centre you choose, the procedure can be quite affordable in India.

ICSI is a procedure that occurs in multiple cycles, each of which has additional costs that must be paid for separately. The minimum ICSI treatment cost in India is Rs. 2,40,000 to Rs. 2,50,000 per cycle. This only includes the standard methods and techniques.

Many couples have been able to conceive healthy babies thanks to assisted reproductive systems. During the treatment cycles, a patient can feel more relaxed with the help of surgical treatment and maintenance. We strongly advise people to take and follow the doctor’s advice, as well as to maintain open and honest communication with the channel. A good working relationship with a specialist can help avoid risks. Doctors will also advise you on precautionary measures that you should take while undergoing the process.

Also, Read: Why Couples Should Opt for IVF

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How Much does an ICSI Treatment Cost in India?

How Much does an ICSI Treatment Cost in India?

August 22, 2022

Infertility has been a problem for...

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While IVF and ICSI might seem like similar procedures, there are several intricacies that make them different. IVF or In Vitro Fertilization is the cycle where the eggs and sperms are put in a laboratory dish to fertilize without any external force. On the other hand, for ICSI or Intracytoplasmic Sperm Injection, a particular sperm is directly injected into the egg.

An ICSI treatment is suitable for any couple where the woman might have had blocked or damaged fallopian tubes, ovulation disorders, endometriosis or adenomyosis or severe pelvic adhesion. It is also suitable for people with a genetic disorder, men with infertility issues like decreased sperm count or sperm motility or any other unexplained infertility issue.

With the ICSI treatment, one can overcome several problems like fertilization by multiple sperm and the inability of the sperm to penetrate the eggs and fertilize them. However, if one has prominent issues with their sperm, like high sperm DNA fragmentation, a history of previous fertilization failure, poor embryo quality, then IMSI or Intracytoplasmic Morphologically Selected Sperm Injection might be a better option.

The IMSI technology uses a high-powered microscope to select a sperm with the best morphology and the lowest fragmentation, so it can easily fertilize the eggs. 

The Process of an ICSI Treatment

The doctor will collect all the eggs of superior quality after the mother undergoes ovarian stimulation for around 9-14 days. These eggs will then be transferred to a temperature-controlled incubator that will also control the humidity and the amounts of various gases that are ideal for the growth of the egg. Once the eggs are allowed to mature for the precise duration of time, an embryologist will mix the mature eggs with the healthy sperm, and the status of fertilization will be determined in 16-18 hours. 

Also, Read: Success Rate of ICSI

How Much Does the ICSI Treatment Cost?

The ICSI treatment can cost anywhere from ₹ 70,000 to ₹ 3,00,000 on an average. However, this does not include the costs for use of donor sperm, donor egg, donor embryo, FET or Frozen Embryo Transfer. You might also have to incur additional costs for the laser assisted hatching of the embryo for boosting implantation, Blastocyst Culture and Transfer, Hysteroscopy, Laparoscopy or Testicular Sperm Retrieval. Each of these procedures can cost you ₹18,000 to ₹80,000. In India, the costs of an ICSI treatment cycle are fraction of the costs for the treatment incurred in other countries. 

Apollo Fertility clinics are present throughout the country, with ICSI center in Chennai, Delhi, Amritsar and most major cities of India. Once you educate yourself about the advantages and setbacks of ICSI treatments, it can prove to be the apt treatment for you and your partner. You can also consult your doctor to be sure of the procedure before you commit to it.

Also, Read: Things You Need to Know About ICSI

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While IVF and ICSI might seem like similar procedures, there are several intricacies that make them different. IVF or In Vitro Fertilization is the cycle where the eggs and sperms are put in a laboratory dish to fertilize without any external force. On the other hand, for ICSI or Intracytoplasmic Sperm Injection, a particular sperm is directly injected into the egg.

An ICSI treatment is suitable for any couple where the woman might have had blocked or damaged fallopian tubes, ovulation disorders, endometriosis or adenomyosis or severe pelvic adhesion. It is also suitable for people with a genetic disorder, men with infertility issues like decreased sperm count or sperm motility or any other unexplained infertility issue.

With the ICSI treatment, one can overcome several problems like fertilization by multiple sperm and the inability of the sperm to penetrate the eggs and fertilize them. However, if one has prominent issues with their sperm, like high sperm DNA fragmentation, a history of previous fertilization failure, poor embryo quality, then IMSI or Intracytoplasmic Morphologically Selected Sperm Injection might be a better option.

The IMSI technology uses a high-powered microscope to select a sperm with the best morphology and the lowest fragmentation, so it can easily fertilize the eggs. 

The Process of an ICSI Treatment

The doctor will collect all the eggs of superior quality after the mother undergoes ovarian stimulation for around 9-14 days. These eggs will then be transferred to a temperature-controlled incubator that will also control the humidity and the amounts of various gases that are ideal for the growth of the egg. Once the eggs are allowed to mature for the precise duration of time, an embryologist will mix the mature eggs with the healthy sperm, and the status of fertilization will be determined in 16-18 hours. 

Also, Read: Success Rate of ICSI

How Much Does the ICSI Treatment Cost?

The ICSI treatment can cost anywhere from ₹ 70,000 to ₹ 3,00,000 on an average. However, this does not include the costs for use of donor sperm, donor egg, donor embryo, FET or Frozen Embryo Transfer. You might also have to incur additional costs for the laser assisted hatching of the embryo for boosting implantation, Blastocyst Culture and Transfer, Hysteroscopy, Laparoscopy or Testicular Sperm Retrieval. Each of these procedures can cost you ₹18,000 to ₹80,000. In India, the costs of an ICSI treatment cycle are fraction of the costs for the treatment incurred in other countries. 

Apollo Fertility clinics are present throughout the country, with ICSI center in Chennai, Delhi, Amritsar and most major cities of India. Once you educate yourself about the advantages and setbacks of ICSI treatments, it can prove to be the apt treatment for you and your partner. You can also consult your doctor to be sure of the procedure before you commit to it.

Also, Read: Things You Need to Know About ICSI

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How is ICSI Different from IVF Treatments? How Much does it Cost?

How is ICSI Different from IVF Treatments? How Much does it Cost?

August 9, 2022

While IVF and ICSI might seem like...

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Intracytoplasmic sperm injection or ICSI is the process of injecting healthy sperm directly into the matured eggs. The ICSI treatment is generally used, along with IVF, when there are repeated IVF cycle failures, and also when the quality or mobility of the semen is a problem in couples trying artificial insemination. The process allows the sperm to be injected directly into the center of the egg. 

What Is the Aim of ICSI?

The ICSI procedure is done with an objective of achieving successful fertilization in couples, where severe male infertility exists. The treatment is also effectively used in situations when the IVF attempts fail two or three times. By injecting the sperm into the center of the egg, the possibility of fertilization is enhanced through ICSI. The failed in vitro fertilization (IVF) attempts made earlier can find ICSI used in conjunction with IVF removes the hindrances of low mobility of the sperm and makes fertilization possible. This gives hope to couples who want to give birth to the baby of their own.

What Is the Procedure of ICSI Treatment?

The ICSI process asks for more matured eggs, so the egg donor need to undergo ovarian stimulation and have fertility medications to stimulate and develop numerous matured eggs.  The matured eggs are retrieved from the follicles with the help of a vaginal ultrasound. Then the eggs are incubated in an embryology laboratory. At the same time, the semen sample is centrifuged or ‘washed” to remove fluids and other impurities and debris of dead sperm through a special medium. This way the most active live sperm is separated and injected into the egg.  The embryologist works on it very carefully with a glass needle to inject the sperm into the center of each egg. 

Also, Read: What is ICSI Infertility Treatment

Who Needs ICSI Treatment?

The ICSI process is necessary for the male factor with infertility and abnormal semen analysis and low sperm mobility, but more than 70 percent of the IVF cases choose ICSI to enhance the chances of successful fertilization. Other than these, ICSI is opted for the reasons such as: 

  • Inconstant sperm counts
  • Poor fertilization result with IVF
  • Unexplained infertility

The patients with any abnormalities in the sperm results should seriously consider doing the ICSI treatment or the male partner, who have undergone vasectomy reversal surgery, he should go for ICSI, regardless of the sperm quality test result as the reason that the antibodies present in the sperm will affect the quality of the sperm and fertilization process. Males with no prior evidence of infertility may also sometimes be suggested to ICSI treatment to have any possibilities of fertilization. In addition, the couples with normal sperm quality and counts can also opt this method to achieve maximum success in fertilization.

Apart From the Male Infertility Cases, ICSI Is a Good Option for Situations:

  • When the previous IVF cycles have very few fertilized eggs. For example, when the previous IVF cycles have no or fewer fertilized eggs notwithstanding there are sufficient matured eggs and disposal of healthy sperm, you will be suggested to go for ICSI with the IVF cycle. This will increase the chances of pregnancy.  
  • When the frozen sperm are used for the IVF cycle, ICSI treatment is recommended as the thawed sperm is not active. Using the ICSI method in frozen sperm gives the same pregnancy success rate as with the fresh ones.
  • For genetic screening using preimplantation genetic diagnosis (PGD). The ICSI procedure is recommended for the IVF method owing to the genetic factors of other sperms present around the embryo. This will not give you the correct result. When ICSI method is used to fertilize the egg, only the genetic factor of the injected sperm will the egg contain. Furthermore, this will reduce the chance of passing problematic genetic condition to the baby.  So, the IVF with PGD procedures suggest only ICSI for fertilization.

What Is the Success Rate of ICSI?

The couples with male factor difficulty have attained a pregnancy rate of more than 70 to 80 percent using the ICSI procedure. More than 7-8 eggs out of 10 injected eggs are fertilized through this method, which is equivalent to the fertilization attained with normal sperm. 

Is There Any Risk Factor Involved in the ICSI Procedure?

There are several risks involved in this procedure. The most significant one is during the needle insertion, where about 5 percentage of eggs may rupture or damage. Next, risk is out of 8 in 1000 babies, who may have some chromosomal abnormality in the X or Y chromosomes.  

Will All the Eggs Be Injected?

When it comes to the ICSI treatment, all matured eggs will be injected with the sperm. This involves as many eggs as possible. The experienced microbiologists can tell you which egg is matured and which is not and will choose the best matured eggs for ICSI.

Also, Read: Things You Need to Know About ICSI

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Intracytoplasmic sperm injection or ICSI is the process of injecting healthy sperm directly into the matured eggs. The ICSI treatment is generally used, along with IVF, when there are repeated IVF cycle failures, and also when the quality or mobility of the semen is a problem in couples trying artificial insemination. The process allows the sperm to be injected directly into the center of the egg. 

What Is the Aim of ICSI?

The ICSI procedure is done with an objective of achieving successful fertilization in couples, where severe male infertility exists. The treatment is also effectively used in situations when the IVF attempts fail two or three times. By injecting the sperm into the center of the egg, the possibility of fertilization is enhanced through ICSI. The failed in vitro fertilization (IVF) attempts made earlier can find ICSI used in conjunction with IVF removes the hindrances of low mobility of the sperm and makes fertilization possible. This gives hope to couples who want to give birth to the baby of their own.

What Is the Procedure of ICSI Treatment?

The ICSI process asks for more matured eggs, so the egg donor need to undergo ovarian stimulation and have fertility medications to stimulate and develop numerous matured eggs.  The matured eggs are retrieved from the follicles with the help of a vaginal ultrasound. Then the eggs are incubated in an embryology laboratory. At the same time, the semen sample is centrifuged or ‘washed” to remove fluids and other impurities and debris of dead sperm through a special medium. This way the most active live sperm is separated and injected into the egg.  The embryologist works on it very carefully with a glass needle to inject the sperm into the center of each egg. 

Also, Read: What is ICSI Infertility Treatment

Who Needs ICSI Treatment?

The ICSI process is necessary for the male factor with infertility and abnormal semen analysis and low sperm mobility, but more than 70 percent of the IVF cases choose ICSI to enhance the chances of successful fertilization. Other than these, ICSI is opted for the reasons such as: 

  • Inconstant sperm counts
  • Poor fertilization result with IVF
  • Unexplained infertility

The patients with any abnormalities in the sperm results should seriously consider doing the ICSI treatment or the male partner, who have undergone vasectomy reversal surgery, he should go for ICSI, regardless of the sperm quality test result as the reason that the antibodies present in the sperm will affect the quality of the sperm and fertilization process. Males with no prior evidence of infertility may also sometimes be suggested to ICSI treatment to have any possibilities of fertilization. In addition, the couples with normal sperm quality and counts can also opt this method to achieve maximum success in fertilization.

Apart From the Male Infertility Cases, ICSI Is a Good Option for Situations:

  • When the previous IVF cycles have very few fertilized eggs. For example, when the previous IVF cycles have no or fewer fertilized eggs notwithstanding there are sufficient matured eggs and disposal of healthy sperm, you will be suggested to go for ICSI with the IVF cycle. This will increase the chances of pregnancy.  
  • When the frozen sperm are used for the IVF cycle, ICSI treatment is recommended as the thawed sperm is not active. Using the ICSI method in frozen sperm gives the same pregnancy success rate as with the fresh ones.
  • For genetic screening using preimplantation genetic diagnosis (PGD). The ICSI procedure is recommended for the IVF method owing to the genetic factors of other sperms present around the embryo. This will not give you the correct result. When ICSI method is used to fertilize the egg, only the genetic factor of the injected sperm will the egg contain. Furthermore, this will reduce the chance of passing problematic genetic condition to the baby.  So, the IVF with PGD procedures suggest only ICSI for fertilization.

What Is the Success Rate of ICSI?

The couples with male factor difficulty have attained a pregnancy rate of more than 70 to 80 percent using the ICSI procedure. More than 7-8 eggs out of 10 injected eggs are fertilized through this method, which is equivalent to the fertilization attained with normal sperm. 

Is There Any Risk Factor Involved in the ICSI Procedure?

There are several risks involved in this procedure. The most significant one is during the needle insertion, where about 5 percentage of eggs may rupture or damage. Next, risk is out of 8 in 1000 babies, who may have some chromosomal abnormality in the X or Y chromosomes.  

Will All the Eggs Be Injected?

When it comes to the ICSI treatment, all matured eggs will be injected with the sperm. This involves as many eggs as possible. The experienced microbiologists can tell you which egg is matured and which is not and will choose the best matured eggs for ICSI.

Also, Read: Things You Need to Know About ICSI

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Procedure and Risks of ICSI Treatment

Procedure and Risks of ICSI Treatment

August 5, 2022

Intracytoplasmic sperm injection o...

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            [blog_title] => ICSI: How Is It Different from IVF
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There are times when couples with infertility problems visit a fertility clinic to seek help for pregnancy. The chances are high that they may be advised to go for intracytoplasmic sperm injection (ICSI) instead of in vitro fertilization (IVF). It is presumed that ICSI has a higher success rate than IVF and in some cases, it is critical to use it for successful pregnancy. Similarly, there are various circumstances that make doctors suggest ICSI.

What Is Intracytoplasmic Sperm Injection (ICSI)?

A woman’s egg requires a man’s sperm for fertilization, and when the sperm joins the egg, fertilization happens. Nevertheless, fertilization normally happens in the fallopian tubes when the sperm cell is successfully attached to the egg cell and joins it by pushing through the outer layer to the cytoplasm. 

When the sperm fails to enter the egg for it cannot swim or penetrate the egg’s outer layer, one needs to undergo a treatment called intracytoplasmic sperm injection or ICSI, which includes a technique of using a holding pipette, a type of glass needle, to inject a single, healthy sperm directly into the egg’s center or cytoplasm. Those couples with acute male factor infertility or previous failed IVF attempts are helped achieve pregnancy by ICSI.

Under the ICSI procedure, the woman partner undergoes fertility medications for ovarian stimulation to develop mature eggs. The eggs are then drawn using vaginal ultrasound through vagina and incubated in the embryology laboratory under conditions conducive for embryos to flourish. Next, the sperm cells using centrifuging is washed to separate the live sperm and prepare the semen sample. Out of this sample, a single live sperm is picked and injected into the egg in the incubation by the embryologist and then, transferred to the woman’s uterus. 

How are ICSI and IVF as Infertility Treatment Procedures Different? 

Both ICSI and IVF treatment procedures are similar from the ovarian stimulation and retrieving of matured eggs from the woman partner or donor for incubation to the sperm collection. The ICSI treatment process differs from here that a single live sperm is directly injected using a glass needle into the uterus by the embryologist. Alternatively, in the IVF procedure, the sperm and eggs are placed in a petri dish in the lab and monitored for fertilization. In both ICSI IVF techniques Once the eggs are fertilized, the best embryo is chosen and implanted in the uterus.

Also, Read: Things You Need to Know About ICSI

When Is ICSI Used?

ICSI is primarily used to treat male-factor infertility, in which case a male partner’s semen does not meet the normal parameters in the count, shape and mobility. The couples who have male-factor issues find this procedure highly beneficial. There are other instances when ICSI is recommended by doctors.

  • When the man cannot produce enough sperm for artificial insemination.
  • The sperm does not move in a normal way or has poor mobility.
  • The male reproductive tract has a blockage that the sperm cannot get out.
  • The woman’s egg fails to fertilize in the conventional IVF technique despite the fact that eggs are of good condition.
  • In cases where normal viable sperm are not available; instead, the sperm are extracted using percutaneous epididymal sperm aspiration (PESA) or testicular sperm aspiration (TESA) procedures.
  • In cases where there are innumerable antibodies in the semen.
  • When using previously frozen eggs.

How Far Is ICSI Successful?

Infertility is an important clinical problem today and about 8-12 percent of couples are affected by it. Among the infertility cases, roughly 40-50 percent is considered to be male-factor infertility. About 2 percent of men is found to have suboptimal sperm parameters, which may be because of the poor sperm motility, low sperm concentration, or abnormal morphology, or a combination of all. ICSI can help overcome this by directly injecting a single sperm into a woman’s egg. 

With ICSI, the sperm is helped overcome many of its natural barriers that it would encounter during fertilization. The procedure is found to be effective in couples, where the male partner has an extremely low sperm count and the likely of fertilization is low using the IVF procedure for the sperm cannot swim to reach the egg. Under the ICSI condition, the success depends on the embryologist finding healthy sperm to inject into the central part of the egg. 

When it comes to treating the male-factor infertility in India, there are the best ICSI Hyderabad hospitals that take care of your need and budget. The ICSI Bangalore treatment centers could cut down the failed fertilization percentage by more than a half, preventing the instances of canceled cycles. For couples with infertility cancelled cycles after the retrieval of eggs are heartbreaking. This is owing to the high cost with every additional cycle, the aggravation of additional cycles, and going without the biological tie of a father by using a donor sperm.

In case you are still confused about the infertility treatment, get in touch with the best ICSI Chennai treatment centers for a free consultation.

Also, Read: Success Rate Of ICSI

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There are times when couples with infertility problems visit a fertility clinic to seek help for pregnancy. The chances are high that they may be advised to go for intracytoplasmic sperm injection (ICSI) instead of in vitro fertilization (IVF). It is presumed that ICSI has a higher success rate than IVF and in some cases, it is critical to use it for successful pregnancy. Similarly, there are various circumstances that make doctors suggest ICSI.

What Is Intracytoplasmic Sperm Injection (ICSI)?

A woman’s egg requires a man’s sperm for fertilization, and when the sperm joins the egg, fertilization happens. Nevertheless, fertilization normally happens in the fallopian tubes when the sperm cell is successfully attached to the egg cell and joins it by pushing through the outer layer to the cytoplasm. 

When the sperm fails to enter the egg for it cannot swim or penetrate the egg’s outer layer, one needs to undergo a treatment called intracytoplasmic sperm injection or ICSI, which includes a technique of using a holding pipette, a type of glass needle, to inject a single, healthy sperm directly into the egg’s center or cytoplasm. Those couples with acute male factor infertility or previous failed IVF attempts are helped achieve pregnancy by ICSI.

Under the ICSI procedure, the woman partner undergoes fertility medications for ovarian stimulation to develop mature eggs. The eggs are then drawn using vaginal ultrasound through vagina and incubated in the embryology laboratory under conditions conducive for embryos to flourish. Next, the sperm cells using centrifuging is washed to separate the live sperm and prepare the semen sample. Out of this sample, a single live sperm is picked and injected into the egg in the incubation by the embryologist and then, transferred to the woman’s uterus. 

How are ICSI and IVF as Infertility Treatment Procedures Different? 

Both ICSI and IVF treatment procedures are similar from the ovarian stimulation and retrieving of matured eggs from the woman partner or donor for incubation to the sperm collection. The ICSI treatment process differs from here that a single live sperm is directly injected using a glass needle into the uterus by the embryologist. Alternatively, in the IVF procedure, the sperm and eggs are placed in a petri dish in the lab and monitored for fertilization. In both ICSI IVF techniques Once the eggs are fertilized, the best embryo is chosen and implanted in the uterus.

Also, Read: Things You Need to Know About ICSI

When Is ICSI Used?

ICSI is primarily used to treat male-factor infertility, in which case a male partner’s semen does not meet the normal parameters in the count, shape and mobility. The couples who have male-factor issues find this procedure highly beneficial. There are other instances when ICSI is recommended by doctors.

  • When the man cannot produce enough sperm for artificial insemination.
  • The sperm does not move in a normal way or has poor mobility.
  • The male reproductive tract has a blockage that the sperm cannot get out.
  • The woman’s egg fails to fertilize in the conventional IVF technique despite the fact that eggs are of good condition.
  • In cases where normal viable sperm are not available; instead, the sperm are extracted using percutaneous epididymal sperm aspiration (PESA) or testicular sperm aspiration (TESA) procedures.
  • In cases where there are innumerable antibodies in the semen.
  • When using previously frozen eggs.

How Far Is ICSI Successful?

Infertility is an important clinical problem today and about 8-12 percent of couples are affected by it. Among the infertility cases, roughly 40-50 percent is considered to be male-factor infertility. About 2 percent of men is found to have suboptimal sperm parameters, which may be because of the poor sperm motility, low sperm concentration, or abnormal morphology, or a combination of all. ICSI can help overcome this by directly injecting a single sperm into a woman’s egg. 

With ICSI, the sperm is helped overcome many of its natural barriers that it would encounter during fertilization. The procedure is found to be effective in couples, where the male partner has an extremely low sperm count and the likely of fertilization is low using the IVF procedure for the sperm cannot swim to reach the egg. Under the ICSI condition, the success depends on the embryologist finding healthy sperm to inject into the central part of the egg. 

When it comes to treating the male-factor infertility in India, there are the best ICSI Hyderabad hospitals that take care of your need and budget. The ICSI Bangalore treatment centers could cut down the failed fertilization percentage by more than a half, preventing the instances of canceled cycles. For couples with infertility cancelled cycles after the retrieval of eggs are heartbreaking. This is owing to the high cost with every additional cycle, the aggravation of additional cycles, and going without the biological tie of a father by using a donor sperm.

In case you are still confused about the infertility treatment, get in touch with the best ICSI Chennai treatment centers for a free consultation.

Also, Read: Success Rate Of ICSI

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ICSI: How Is It Different from IVF

ICSI: How Is It Different from IVF

August 1, 2022

There are times when couples with ...

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            [blog_title] => ICSI Or Regular Insemination: Which Is the Better Option
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IVF is one of the several infertility treatments available, and one of the most popular ones as well. However, standard IVF steps may not be enough for everyone who has opted for the treatment. Within the treatment, there are at least two modes of insemination available. The first is regular, conventional insemination that is allowing the natural fertilisation process in a lab setting. The second is the ICSI treatment or intracytoplasmic sperm injection.

What is ICSI?

ICSI procedure involves injecting a carefully selected single sperm from the semen sample and injecting it into a single egg. This can be done for multiple eggs.

The procedure is usually recommended in the following cases:

  • Unhealthy sperm
  • Poor sperm motility
  • Issues in sperm attaching to the egg
  • Low sperm count
  • Conventional insemination failure

Depending on the individual case, doctors may also recommend ICSI in cases of unexplained infertility, or any other situation where it may seem like a suitable solution.

Furthermore, ICSI may also fail due to damaged eggs. In some cases, it may achieve fertilisation, but the embryo may stop developing. If the fertilisation and embryo development is successful, the chances of a full-term pregnancy are akin to conventional insemination.

Also, Read: Success Rate Of ICSI

What is Conventional Insemination?

Regular insemination is the default choice in the IVF procedure unless conditions for its failure are noticed. This is the kind of insemination that happens naturally in the female reproductive system. As a part of IVF, it is replicated in a laboratory. The eggs are left with the sperm in a petri dish allowed to fertilise under healthy conditions. However, several health issues may cause this to fail, thus the participants seeking more ways of achieving fertilisation.

Also, Read: Things You Need to Know About ICSI

Is ICSI for you?

Your healthcare specialist can best determine if ICSI would be necessary or helpful for you. Both types of inseminations work in different cases and one cannot be claimed as uniformly better than the other. As mentioned, it is best suited for male factor infertility and failure in conventional insemination. Additionally, it may also help avoid the passing of some genetic or birth defects to the offspring. 

Remember, this process adds to the cost of your IVF treatment. It is best to discuss the outcome of the treatment with your doctor.

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IVF is one of the several infertility treatments available, and one of the most popular ones as well. However, standard IVF steps may not be enough for everyone who has opted for the treatment. Within the treatment, there are at least two modes of insemination available. The first is regular, conventional insemination that is allowing the natural fertilisation process in a lab setting. The second is the ICSI treatment or intracytoplasmic sperm injection.

What is ICSI?

ICSI procedure involves injecting a carefully selected single sperm from the semen sample and injecting it into a single egg. This can be done for multiple eggs.

The procedure is usually recommended in the following cases:

  • Unhealthy sperm
  • Poor sperm motility
  • Issues in sperm attaching to the egg
  • Low sperm count
  • Conventional insemination failure

Depending on the individual case, doctors may also recommend ICSI in cases of unexplained infertility, or any other situation where it may seem like a suitable solution.

Furthermore, ICSI may also fail due to damaged eggs. In some cases, it may achieve fertilisation, but the embryo may stop developing. If the fertilisation and embryo development is successful, the chances of a full-term pregnancy are akin to conventional insemination.

Also, Read: Success Rate Of ICSI

What is Conventional Insemination?

Regular insemination is the default choice in the IVF procedure unless conditions for its failure are noticed. This is the kind of insemination that happens naturally in the female reproductive system. As a part of IVF, it is replicated in a laboratory. The eggs are left with the sperm in a petri dish allowed to fertilise under healthy conditions. However, several health issues may cause this to fail, thus the participants seeking more ways of achieving fertilisation.

Also, Read: Things You Need to Know About ICSI

Is ICSI for you?

Your healthcare specialist can best determine if ICSI would be necessary or helpful for you. Both types of inseminations work in different cases and one cannot be claimed as uniformly better than the other. As mentioned, it is best suited for male factor infertility and failure in conventional insemination. Additionally, it may also help avoid the passing of some genetic or birth defects to the offspring. 

Remember, this process adds to the cost of your IVF treatment. It is best to discuss the outcome of the treatment with your doctor.

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ICSI Or Regular Insemination: Which Is the Better Option

ICSI Or Regular Insemination: Which Is the Better Option

July 28, 2022

IVF is one of the several infertil...

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Before a man’s sperm is able to fertilize a woman’s egg, the head of the sperm must confer to the outside of the egg. Once it is attached, the sperm thrusts through the outer layer to the inside of the egg (cytoplasm), where fertilization happens.

Sometimes the sperm is unable to penetrate the outer layer, for one or many reasons. The egg’s outer layer might be thick or hard to penetrate or the sperm may be incapable of swimming. In these scenarios, a technique known as intracytoplasmic sperm injection (ICSI) can be performed in combination with in vitro fertilization (IVF) to fertilize the egg. During ICSI, a single sperm is injected into the cytoplasm (the egg).

How Does ICSI Treatment Work?

There are two ways that an egg might be fertilized by IVF: traditional and ICSI. In traditional IVF, 50,000 or more swimming sperms are positioned next to the egg in a laboratory dish. Fertilization happens when one of the sperms enters the cytoplasm of the egg. With ICSI treatment, a tiny needle, known as a micropipette, is used to insert a single sperm into the centre of the egg. With either traditional IVF or ICSI, once fertilization happens, the fertilized egg (now called an embryo) grows in a laboratory for 1-5 days before it is transported to the woman’s uterus (womb).

Who will Need ICSI?

ICSI helps to solve fertility problems, such as:

  • Low quantity of sperm for artificial insemination [intrauterine insemination (IUI)] or IVF.
  • Unnatural movement of sperm
  • Egg-attachment issues faced by the sperm
  • Blockage in the male reproductive tract that keeps the sperm from releasing
  • Non-fertilization of eggs by traditional IVF, irrespective of the condition of the sperm.

Does ICSI Work?

ICSI fertilizes 50%-80% of eggs. However, the following problems may be encountered during or after ICSI treatment:

  • Some or all the eggs may turn out to be spoiled.
  • The egg may not grow into an embryo even after it is inoculated with the sperm.
  • The embryo may stop developing.

Once fertilization happens, a couple’s chance of giving birth to a single baby, twins, or triplets is similar to that of IVF with or without ICSI.

Also, Read: Success Rate Of ICSI

Can ICSI impact Baby’s Development?

If a woman gets pregnant on her own, there is a 1.5% to 3% chance that the child will have a major birth defect. The probability of birth defects linked with ICSI is like IVF, but slightly higher than that of natural pregnancy.

The somewhat higher risk of birth defects may be due to the infertility and not the treatments used to treat the infertility. 

Some conditions have been linked with the use of ICSI, such as Beckwith-Wiedemann syndrome, sex chromosome abnormalities, Angelman syndrome, or hypospadias. They are thought to happen in far less than 1% of children conceived using this method.

Some of the issues that cause infertility might be genetic. For instance, male children conceived through ICSI might have the same infertility problems as their fathers.

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Before a man’s sperm is able to fertilize a woman’s egg, the head of the sperm must confer to the outside of the egg. Once it is attached, the sperm thrusts through the outer layer to the inside of the egg (cytoplasm), where fertilization happens.

Sometimes the sperm is unable to penetrate the outer layer, for one or many reasons. The egg’s outer layer might be thick or hard to penetrate or the sperm may be incapable of swimming. In these scenarios, a technique known as intracytoplasmic sperm injection (ICSI) can be performed in combination with in vitro fertilization (IVF) to fertilize the egg. During ICSI, a single sperm is injected into the cytoplasm (the egg).

How Does ICSI Treatment Work?

There are two ways that an egg might be fertilized by IVF: traditional and ICSI. In traditional IVF, 50,000 or more swimming sperms are positioned next to the egg in a laboratory dish. Fertilization happens when one of the sperms enters the cytoplasm of the egg. With ICSI treatment, a tiny needle, known as a micropipette, is used to insert a single sperm into the centre of the egg. With either traditional IVF or ICSI, once fertilization happens, the fertilized egg (now called an embryo) grows in a laboratory for 1-5 days before it is transported to the woman’s uterus (womb).

Who will Need ICSI?

ICSI helps to solve fertility problems, such as:

  • Low quantity of sperm for artificial insemination [intrauterine insemination (IUI)] or IVF.
  • Unnatural movement of sperm
  • Egg-attachment issues faced by the sperm
  • Blockage in the male reproductive tract that keeps the sperm from releasing
  • Non-fertilization of eggs by traditional IVF, irrespective of the condition of the sperm.

Does ICSI Work?

ICSI fertilizes 50%-80% of eggs. However, the following problems may be encountered during or after ICSI treatment:

  • Some or all the eggs may turn out to be spoiled.
  • The egg may not grow into an embryo even after it is inoculated with the sperm.
  • The embryo may stop developing.

Once fertilization happens, a couple’s chance of giving birth to a single baby, twins, or triplets is similar to that of IVF with or without ICSI.

Also, Read: Success Rate Of ICSI

Can ICSI impact Baby’s Development?

If a woman gets pregnant on her own, there is a 1.5% to 3% chance that the child will have a major birth defect. The probability of birth defects linked with ICSI is like IVF, but slightly higher than that of natural pregnancy.

The somewhat higher risk of birth defects may be due to the infertility and not the treatments used to treat the infertility. 

Some conditions have been linked with the use of ICSI, such as Beckwith-Wiedemann syndrome, sex chromosome abnormalities, Angelman syndrome, or hypospadias. They are thought to happen in far less than 1% of children conceived using this method.

Some of the issues that cause infertility might be genetic. For instance, male children conceived through ICSI might have the same infertility problems as their fathers.

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ICSI Treatment: Here's All You Need to Know

ICSI Treatment: Here's All You Need to Know

July 22, 2022

Before a man’s sperm is able to ...

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