A Comprehensive Overview of Laser Assisted Hatching (LAH)

What is Laser Assisted Hatching (LAH)?

Laser Assisted Hatching (LAH) is used in assisted reproduction to improve the chances of an IVF cycle working. It is a new technology that uses a laser to make a small hole in an embryo's "zona," or outer shell. This opening, or "hatch," makes it easier for the embryo to attach to the uterine wall and start a pregnancy.

Who qualifies for Laser Assisted Hatching (LAH)?

LAH is a therapy that reduces the risks associated with other procedures, such as IVF. If your doctor feels you are having difficulty conceiving, they may offer Laser Assisted Hatching as a kind of assisted reproduction.

LAH treats a variety of reproductive problems, such as:

  • LAH can be used if the zona pellucida, which is the outside shell of the embryo, is thickened or stiffened.
  • LAH is suggested if the embryo is having difficulties hatching on its own.
  • LAH is suggested for older women who have a high level of follicle-stimulating hormone (FSH) or a history of poor-quality embryos.

What is the procedure of Laser Assisted Hatching (LAH)?

Before going ahead with a process, there are some preparations you should undertake. Some points to consider before Laser Assisted Hatching (LAH):

  • You should have an ultrasound to determine the number of embryos, size, shape, and location(s).
  • Your doctor will be able to decide the most effective method for hatching them with this information.
  • Inquire about any drugs, such as antibiotics or steroids, that you must take before or after LAH.

Only a trained specialist must carry it out to reduce the likelihood of the embryo being harmed during the process since it calls for a high degree of expertise and accuracy. The procedure for Laser Assisted Hatching (LAH) typically involves the following steps:

Selection of Embryos: Before beginning the treatment, the specialist will choose those embryos that have the characteristics necessary for LAH. Typically, these embryos have reached the blastocyst stage, which occurs around five to six days after fertilisation.

Preparation of the embryo for LAH: The embryo used is carefully removed from the incubator and put under a microscope.

Laser treatment: The zona pellucida is targeted with a laser beam, creating a slit or a tiny hole in the outer shell. In most cases, the diameter of the hole is far less than 10 mm. The laser used in the procedure is precise, and the energy used is carefully controlled to minimise the risk of damage to the embryo.

Hole inspection: The embryo is examined under a microscope to check that the hole is of the correct size and shape. This is to ensure that the embryo is not injured during the process.

Embryo Transfer: As part of the in vitro fertilisation (IVF) process, the embryo is moved to the uterus after the Laser Assisted Hatching (LAH) procedure.

Benefits of the Laser Assisted Hatching (LAH) procedure

The following are some of the benefits of LAH:

  •  Increases the rate of embryo implantation
  •  Increases the likelihood of pregnancy in elderly women
  • Increased rates of live births
  • Encourages the development of egg embryos

Risks of Laser-Assisted Hatching (LAH)

The following are some of the potential risks of LAH:

  • Possibility of embryo harm from the laser beam
  • The laser beam may produce many apertures, compromising the zona pellucida's integrity.
  • There is a danger of contamination, which might result in infection.
  • LAH may raise the chance of an ectopic pregnancy in rare circumstances, which happens when the fertilised egg implants outside the uterus.

Concerns about Laser Assisted Hatching (LAH) include possible cell damage and an increased risk of miscarriage. Nonetheless, these are rare occurrences, and most patients report no adverse effects following laser-assisted hatching.


LAH is a practical and safe choice for couples seeking a reproductive solution. It has been demonstrated to boost IVF success while causing no significant adverse effects. You may improve your odds of having a successful pregnancy by combining reproductive technologies such as laser-assisted hatching (LAH) with lifestyle adjustments.

Couples who wish to learn about LAH can speak with a specialist at Apollo Fertility's Solapur Clinic. For a consultation, call 1860-500-4244.

1. How does LAH work?

LAH includes the employment of a laser beam to generate a tiny hole or slit in an embryo's zona pellucida. The treatment is usually carried out by a highly trained professional who employs specific equipment and skills.

2. Is it safe to use LAH?

While certain risks are associated with LAH, it is usually considered a safe technique. These dangers include embryo injury, contamination, and ectopic pregnancy.

3. Who is a candidate for LAH?

People who have had a lot of failed IVF cycles, have a disease that might be stopping the embryo from implanting, or have a zona pellucida that is too thick may benefit from LAH.

4. How successful is LAH?

The success rate of Laser Assisted Hatching (LAH) varies according to the individual's circumstances. Studies have proven LAH to improve the likelihood of successful implantation, pregnancy, and live delivery following IVF, especially in specific instances.

5. What may I expect after having LAH?

The embryo will be transplanted to the uterus as part of the IVF procedure after undergoing LAH. Patients should follow their healthcare provider's recommendations and continue to monitor their symptoms, reporting any concerns or difficulties to their healthcare team.

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